Holte led Laguna with 11 kills, Palmer had 14 assists, Greenough had three kills and Chanel Stewart had six kills.
Laguna has had its way against Estancia throughout the years. With Tuesday's win, the Breakers improved to 39-0 all-time against the Eagles in best-of-five matches.
Laguna, ranked fifth in CIF Division 1-A, faces a stiff challenge Saturday when it takes on Long Beach Poly in the Steve Lewis Festival at Lakewood High. The Breakers and Jackrabbits, ranked second in Division 1-AA, meet at 4 p.m.
"They're tough," Stewart said of the Jackrabbits. "They jump really well and a quick and athletic. If they have a weakness, it's ball control. But they make up for that with their athleticism."
Next week, Laguna returns to league play. The Breakers host Godinez Tuesday and play at Costa Mesa on Thursday. Both matches begin at 5:45 p.m.
Laguna Beach was dominant Sept. 30 in its Orange Coast League match against Calvary Chapel, coming away with a 15-3 home court victory.
Seniors Bianca Sganga and Haley Moss swept in singles and the teams of Kate Rogers/Katelyn Walsh and Lia Berger/Parker Poche' swept in doubles.
The Breakers improved to 2-0 in league and evened their overall mark at 4-4.
Rain washed out Tuesday's home league match against Godinez and Wednesday's nonleague match at Santa Margarita.
Next week, the Breakers are home Tuesday to Saddleback and on the road Thursday at Estancia in league action.
The Orange Coast League Cluster Meet was held Sept. 30 at Centennial Park in Santa Ana and the Laguna Beach girls finished first and the boys second in the varsity competitions.
The cluster included Laguna Beach, Calvary Chapel, Costa Mesa, Estancia, Godinez and Saddleback.